The Province of Nueva Vizcaya is located in the heart of Northern Luzon. It is geographically located at eh southernmost part of Region II and is often referred to as the gateway to vast Cagayan Valley region. It is bounded on the north of Ifugao, in the northeast of Isabela, east by quirino, west by Benguet and south by Nueva Ecija.

Air-conditioned buses (Baliwag Transit, Victory Liner, etc.) bound for Cagayan Valley pass by the province. For independent motorists, take the North Luzon Expressway and exit at Sta. Rita. Nueva Vizcaya is accessible through the Cagayan Valley Road (Daang Maharlika) and is about 268 km north of Metro Manila (approx. 6hrs of travel by land).

Buses and public utility jeepneys ply the routes around the province. Tricycles are numerous in every town. Van/Car rental services are available with rates depending on the type of vehicles used and the distance traveled.